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Hiromi Sugimoto Selected Research

ramatroban

11/2003Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats.
4/2003An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro.

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Hiromi Sugimoto Research Topics

Disease

2Inflammation (Inflammations)
01/2018 - 07/2004
2Eosinophilia
11/2003 - 04/2003
1Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2020
1Fibrosis (Cirrhosis)
01/2020
1Idiopathic Pulmonary Fibrosis
01/2018
1Hepatocellular Carcinoma (Hepatoma)
01/2018
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2018
1Liver Neoplasms (Liver Cancer)
01/2018
1Neoplasms (Cancer)
01/2018
1Chronic Disease (Chronic Diseases)
12/2011
1Pneumonia (Pneumonitis)
12/2011
1Motor Disorders
05/2009
1Hypersensitivity (Allergy)
02/2008
1Osteosarcoma (Osteogenic Sarcoma)
12/2005
1Pain (Aches)
12/2005
1Atopic Dermatitis (Atopic Eczema)
07/2004
1Contact Dermatitis (Eczema, Contact)
07/2004
1Lymphoma (Lymphomas)
11/2003
1Allergic Rhinitis
04/2003

Drug/Important Bio-Agent (IBA)

2pirfenidoneIBA
01/2020 - 01/2018
2ProstaglandinsIBA
07/2004 - 04/2003
2Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
07/2004 - 11/2003
2Prostaglandins DIBA
07/2004 - 04/2003
2ramatrobanIBA
11/2003 - 04/2003
1CytokinesIBA
01/2020
1Hydroxyproline (4 Hydroxyproline)IBA
01/2020
1Pharmaceutical PreparationsIBA
01/2018
1Extracellular Matrix ProteinsIBA
01/2018
1CollagenIBA
01/2018
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
01/2018
1SmokeIBA
12/2011
14- ((4- ((((3- Isopropyl- 2- oxo- 2,3- dihydro- 1H- benzimidazol- 1- yl)carbonyl)amino)methyl)piperidin- 1- yl)methyl)tetrahydro- 2H- pyran- 4- carboxylic acidIBA
05/2009
1Analgesics (Analgesic Drugs)IBA
02/2008
1N- ((1S)- 1- (aminocarbonyl)- 2,2- dimethylpropyl)- 3- (3- hydroxy- 3- methylbutyl)- 2- oxo- 2,3- dihydro- 1H- benzimidazole- 1- carboxamideIBA
02/2008
1CannabinoidsIBA
02/2008
1LigandsIBA
02/2008
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
12/2005
1Biological ProductsIBA
12/2005
1Eicosanoid Receptors (Eicosanoid Receptor)IBA
12/2005
1Cyclic AMP (AMP, Cyclic)IBA
12/2005
1Epoprostenol (Prostacyclin)FDA LinkGeneric
12/2005
1Fluorescein-5-isothiocyanate (FITC)IBA
07/2004
1Chemotactic FactorsIBA
07/2004
1ChemokinesIBA
07/2004
1CalciumIBA
11/2003
1Prostaglandin H2 Thromboxane A2 ReceptorsIBA
11/2003
1Prostaglandin D2IBA
11/2003
1AntigensIBA
04/2003
1ThromboxanesIBA
04/2003

Therapy/Procedure

1Ligation
07/2004
1Intranasal Administration
04/2003